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Subperiosteal Schwannoma of the Humerus: A Case Report and Review of Literature

Submission Type:Case Study

1 Department of radiology, King Fahad specialist hospital-Dammam

2 Department of radiology, King Fahad specialist hospital-Dammam

3 Department of pathology, King Fahad specialist hospital-Dammam

4 Department of orthopedic surgery, King Fahad specialist hospital-Dammam

Abstract

There are numerous conditions that arise from the surface of bones including both neoplastic and non-neoplastic entities. Schwannoma had been reported to be one of those conditions originating from the bone surface with variable proposed theories on it’s origin. We present a unique case of subperiosteal schwannoma arising from the humerus in a 40 years old female with history of painful swelling for two years. Radiograph showed cortically based lytic lesion located in the lateral distal humeral metaphysis with periosteal reaction and cortical scalloping. MRI showed the same juxtacortical lesion with a large extraosseous soft tissue component. It demonstrates intermediate T1 signal intensity and high signal intensity on T2 weighted images with intense enhancement. US guided biopsy showed benign peripheral nerve sheath tumour, consistent with schwannoma. The patient underwent complete rescetion with no complications or documented recurrence till the latest follow-up. In conclusion, subperiosteal schwannoma should be kept in the differential diagnosis in patients presenting with bone surface lesions associated with unexplained vague pain and swelling for a prolonged period of time.

Main Subjects

Training
Radiological Education
Quality Assurance
+4

Keywords

Elbow pain
schwannoma
subperisoteal
juxtacortical schwannoma.

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2, 1st Issue

Pages 22 - 30

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References

  1. 1.
    Kawasaki G, Yanamoto S, Yoshida H, Mizuno A, Fujita S, Ikeda T. Intraosseous Schwannoma of the Mandibular Symphysis: Report of a Case. Oral Science Inter- national. 2010;7(2):76–9.
  2. 2.
    Corfas G. Mechanisms and Roles of Axon-Schwann Cell Interactions. The Journal of Neuroscience. 2004;24(42):9250–60.
  3. 3.
    Knight DMA, Birch R, Pringle J. Benign solitary schwannomas. The Journal of Bone and Joint Surgery British volume. 2007;89-B(3):382–7.
  4. 4.
    Verma R, Khan MS, Am D, Mangham DC, Grimer RJ. Subperiosteal schwannomas of the femur. Skeletal Radiology. 2002;31(7):422–5.
  5. 5.
    Andrew SM, Freemont AJ. Juxtacortical malignant schwannoma with heterologous elements. Histopathology; 1993.
  6. 6.
    Kenan S, Abdelwahab IF, Klein ML, Hermann G, Lewis M. Lesions of juxtacortical origin (surface lesions of bone). Skeletal Radiology. 1993;22(5).
  7. 7.
    Seeger LL, Yao L, Eckardt JJ. Surface lesions of bone. Radiology. 1998;206(1):17–33.
  8. 8.
    Baehring JM, Betensky RA, Batchelor TT. Malignant peripheral nerve sheath tumor. Neurology. 2003;61(5):696–8.
  9. 9.
    Santos PP de A, Freitas VS, Pinto LP, de Freitas AR, de Souza LB. Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature. Annals of Diag- nostic Pathology. 2010;14(4):235–9.
  10. 10.
    Park YK, Kim YW, Yang MH, Kim EJ, Ryu DM. Neurilemmoma of the mandible. Skeletal Radiology. 1999;28(9):536–9.
  11. 11.
    de Lacerda SA, Brentegani LG, Rosa AL, Vespúcio MVO, Salata LA. Intraosseous schwannoma of mandibular symphysis: case report. Brazilian Dental Journal. 2006;17(3):255–8.
  12. 12.
    Patro BP, Das SS, Behera S, Amrit G, Patra SK, Kumar DS. Subperiosteal Schwan- noma: A Rare Cause of Unexplained Pain Around the Knee. EJMO. 2020;4(1):54–59.
  13. 13.
    Lakhotia D, Jeph S, Sharma S. Subperiosteal Schwannoma of Pelvis- A Rare Case and Review of Literature. Journal of Clinical and Diagnostic Research; 2016.
  14. 14.
    Singh VA, Grimer R. Subperiosteal Schwannoma Of The Ulna. The Internet Journal of Orthopedic Surgery. 2006;3(1).
  15. 15.
    Moussa MK, El-Yahchouchi CA, Lahoud JC, Moussallem CD. Subperiosteal Schwan- noma of the Mid-Tibia: A Cause of Long-Lasting Unexplained Pain. Cureus; 2020.
  16. 16.
    Al-Lhedan F. Schwannoma of the femur: A rare case report. Journal of Bone Oncol- ogy. 2017;8:1–3. [cited 2019 Jul 30]. Available from: https://www.sciencedirect.com/ science/article/pii/S2212137417300519.
  17. 17.
    Julfiqar AM, Huda N, Pant A. Giant Ancient Solitary Schwannoma Masquerading as Juxtacortical Osteosarcoma of Femur-A Rare Case Report and Literature Review. Journal of Bone and Soft Tissue Tumors. 2019;5(1):28–30.